New depression type affects 1 in 4 patients

Scientists have discovered a subtype of depression called "Circadian Rhythm-Related Depression," which is linked to disruptions in the body's biological clock and affects the regulation of sleep and wakefulness. Approximately 25% of individuals with depression are affected by this type, which is often characterized by symptoms such as increased sleep hours, fatigue upon awakening, insomnia, and an earlier age of onset with more severe symptoms. This subtype tends to be more resistant to traditional treatments like selective serotonin reuptake inhibitors (SSRIs), but responds well to therapies aimed at regulating the biological clock, such as melatonin and light therapy. Studies indicate that early diagnosis of this type is important to prevent treatment failure and reduce side effects, and identifying it helps in choosing more effective treatments.

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