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RA medication also treats alopecia
Two phase III clinical trials have shown that the drug "Opagacitinib," used for immune-related diseases, may help restore hair growth in patients with severe alopecia areata. The study involved 1,399 adolescents and adults who had lost at least half of their scalp hair, and the results indicated that approximately 50% of those taking a 15 mg dose regained at least 80% of their hair, while the percentage increased to over 54% among those taking a 30 mg dose, compared to just 2% in the placebo group. Additionally, around 13% of participants on the 15 mg dose and 23% on the 30 mg dose experienced complete hair recovery on the scalp, with more than half of the participants on the higher dose also showing improvements in eyebrow and eyelash growth. The medication belongs to the class of JAK inhibitors, which reduce the activity of immune pathways attacking hair follicles. Signs of improvement appeared within eight weeks, with common side effects including acne, colds, and upper respiratory infections. However, ongoing assessments are necessary to evaluate the long-term safety and effectiveness.
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